"It will be the doers and grafters, the inventors and the entrepreneurs who get this economy going," Mr Cameron said - pledging to slash red tape that stands in the way of enterprise.
"Right now in our country there are what I would call the enemies of enterprise, whether it's bureaucrats who concoct ridiculous rules or town hall officials who take ages to make planning decisions. Believe me, we are taking them on," he said.
In practical terms, Mr Cameron said he plans to cut corporation tax and introduce an enterprise allowance to help unemployed potential-entrepreneurs set up their business.
"So I can tell you today, the Budget in a few weeks time will tear down the barriers of enterprise and be the most pro-growth Budget this government, this country has seen for a generation," he said.
The thoughts of the Prime Minister are shared by Business Secretary Vince Cable who has come under criticism for failing to provide a guideline for economic growth in the run up to the Budget on March 23.
According to The Telegraph, Mr Cable said that the on-going Growth Review was: "an exercise every bit as rigorous and challenging as its spending equivalent."
Even though the government is confident of stimulating enterprise, recent statistics mean they will have their work cut out for them.
According to the Department for Business, Innovation and Skills, there was an increase of 51,000 private sector enterprise in the UK in 2009 (the latest available figures), bringing the total up to 4.8 million, the highest since records began in 1994. However, employment fell by 309,000 since the start of 2008. And estimated employment in SMEs fell by 102,000 to 13.6 million people at the start of 2009. Meaning that even though we have more businesses being set up - they are not providing enough employment opportunities to take up the slack from the public sector.
Over the next few weeks, in the lead up to the Budget, Mr Cable has said that we should see more concrete details emerge of how the government plans to help foster enterprise in the country.
"Our central task is to strengthen a framework in which the private sector can grow the economy out of its current problems; and to do so without returning to credit-financed private consumption, a dangerous property bubble and unsustainable government deficit financing," he said.